| 27. Dr. Jones is collaborating with a clinical trial, and receives $300 for every patient he enrolls. This is intended to cover the additional administrative costs he incurs. |
| # | Response Date | Comment |
| 1. | Tue, 3/13/07 11:01 PM | Is the $300 in place of other sources of funding for the administrative costs? If so, then seems reasonable (if not in his pocket directly). |
| 2. | Tue, 3/13/07 11:35 PM | Whether this accurately reflects the administrative costs |
| 3. | Wed, 3/14/07 12:23 AM | if cost at this level is actually incurred |
| 4. | Wed, 3/14/07 12:31 AM | If $300 approximates his clinic overhead for each patient that he enrolls - staff time, lost clinic time otherwise for non-trial patients, then there is no COI. |
| 5. | Wed, 3/14/07 12:34 AM | If that is the administrative cost, no COI. If the cost is much less, then there is a moderate COI |
| 6. | Wed, 3/14/07 12:36 AM | Is the $300 an appropriate amount to cover actual costs? |
| 7. | Wed, 3/14/07 2:31 AM | on whether $300 reflects the real costs he incurs or if it is inflated to encourage him to pressure patients to enroll |
| 8. | Wed, 3/14/07 3:26 AM | No COI providing this does not lead to excessive coersion of patients and that all enrolled patients fall within the eligibility criteria. |
| 9. | Wed, 3/14/07 12:59 PM | potential but can be mitigated with strict inclusion/exclusion criteria, someone else doing recruitment and enrollment, etc |
| 10. | Wed, 3/14/07 2:24 PM | How money is received..directly into fund for soley for study administration or otherwise and actual cost of adminstration per patient |
| 11. | Wed, 3/14/07 2:35 PM | Not a conflict if the money does not go to him personally but to an account set up separately to handle administrative costs. |
| 12. | Thu, 3/15/07 2:41 PM | Depends on costs to the office of administering the study |
| 13. | Mon, 3/19/07 4:24 PM | This is now standard practice as a finder fee.As long as appropriate recruitment procedures are maintained, then no conflict occurs. |
| 14. | Mon, 3/19/07 5:38 PM | Does it? |
| 15. | Mon, 3/19/07 8:56 PM | This is acceptable as long as the fee covers actual clinical or administrative costs. When it goes beyond this (as below) to reward the physician for enrollong possibly inappropriate study patients, it reducec the impartiality and value of the study. |
| 16. | Mon, 3/26/07 3:22 PM | depends on how well that amount corresponds with the administrative costs, and on the procedures in place to ensure that patients engage in fully informed consent. |
| 17. | Thu, 3/29/07 1:42 PM | depends on actual costs |
| 18. | Mon, 4/23/07 1:35 PM | If this reflects the costs incurred than it is reasonable. |
| 19. | Tue, 4/24/07 2:02 PM | Comes down to cost incured with enrollment. $300 seems reasonable for time/effort etc. So, small COI. |
| 20. | Tue, 4/24/07 10:02 PM | No, if this is reasonable for his incurred costs. |
| 21. | Thu, 4/26/07 12:32 PM | if clear selection criteria are developed by panel of experts and approved by human subjects review board then problem is minimized |
| 22. | Mon, 4/30/07 2:19 AM | He should not receive money in excess of his costs. |
| 23. | Tue, 5/8/07 12:08 AM | Needs to be determined appropriate by the IRB. |
| 24. | Tue, 5/8/07 3:31 PM | .... |
| 25. | Tue, 5/15/07 4:37 PM | If the referrals to the trial are legitmate, there is less of a COI. |